NCBI STATPEARLS + PUBMED + OPEN-I VERIFIED SEED TAXONOMY
Medipaedia.org Master Clinical Topic Taxonomy (By Specialty & ICD-10/11)
Standardized 10-Section High-Yield Clinical Reference Matrix across 19 Medical Specialties with verified ICD-10/11 codes, Classic Triads, Gold-Standard Diagnostic Tests, and First-Line Treatment Protocols.
All 19 Specialties (60)CardiologyRespiratoryGastroenterology & HepatologyNephrology & UrologyNeurologyEndocrinology & MetabolismHaematology & OncologyInfectious DiseasesRheumatology & ImmunologyEmergency Medicine & Critical CareGeneral & Specialty SurgeryPaediatricsObstetrics & GynaecologyDermatologyPsychiatryOphthalmology & ENTPathology & Laboratory MedicineMusculoskeletal & TraumaRadiology & Medical Imaging
| # | Topic, Specialty & ICD-10/11 | Classic Triad / Key Presentation | Gold-Standard Diagnostic Test | First-Line Treatment Protocol | Status |
|---|---|---|---|---|---|
| 17 |
Acute pancreatitis
ICD-10: K85.9
ICD-11: DC31
Gastroenterology & Hepatology
|
Revised Atlanta Criteria (≥2 of 3): Severe epigastric pain radiating to the back + Serum lipase/amylase ≥3× ULN + Characteristic CECT/MRI pancreatitis findings | Serum Lipase (more specific and stays elevated longer than amylase) + Right Upper Quadrant Ultrasound (to detect gallstones) | Goal-directed balanced crystalloid resuscitation (Ringer's Lactate) + Multimodal analgesia + Early oral/enteral nutrition within 24–48h + Index laparoscopic cholecystectomy if gallstone-induced | ✓ Published (mID 10006) |
| 18 |
Spontaneous bacterial peritonitis
ICD-10: K65.2
ICD-11: DB99.7
Gastroenterology & Hepatology
|
Ascites in cirrhotic patient + Fever / Diffuse abdominal tenderness + Hepatic encephalopathy or acute kidney injury (often asymptomatic in 30%) | Diagnostic Paracentesis showing Ascitic Fluid Absolute Polymorphonuclear (PMN / Neutrophil) count ≥250 cells/mm³ (≥0.25 × 10⁹/L) | Empiric IV 3rd-generation Cephalosporin (Cefotaxime 2 g q8h or Ceftriaxone 2 g OD for 5 days) + IV Albumin (1.5 g/kg on Day 1 and 1.0 g/kg on Day 3 to prevent Hepatorenal Syndrome) | ✓ Published (mID 10025) |
| 19 |
Acute cholangitis
ICD-10: K83.0
ICD-11: DC12.0
Gastroenterology & Hepatology
|
Charcot's Triad: Fever with rigors + Right upper quadrant pain + Obstructive jaundice (Reynolds' Pentad adds: Septic shock + Confusion/altered mental status) | Tokyo Guidelines (systemic inflammation + cholestasis + biliary dilatation/choledocholithiasis on RUQ Ultrasound, MRCP, or EUS) | IV broad-spectrum antibiotics (Piperacillin-tazobactam or Ceftriaxone + Metronidazole) + Crystalloid resuscitation + Urgent biliary decompression via ERCP within 24–48 hours | ✓ Published (mID 10026) |
| 20 |
Upper gastrointestinal bleeding
ICD-10: K92.2
ICD-11: ME24.90
Gastroenterology & Hepatology
|
Haematemesis (red blood or coffee-ground emesis) + Melaena (black, tarry stools) + Haemodynamic instability / elevated urea-to-creatinine ratio | Oesophagogastroduodenoscopy (OGD / EGD) within 24 hours (within 12 hours if suspected variceal bleed) + Glasgow-Blatchford Score risk stratification | Restrictive RBC transfusion (threshold Hb <70 g/L) + Non-variceal: Endoscopic therapy (clips/adrenaline/thermal) + IV PPI; Variceal: IV Terlipressin/Octreotide + IV Ceftriaxone + Endoscopic variceal band ligation | ✓ Published (mID 10027) |